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. 2020 Feb 27;11(3):257. doi: 10.3390/genes11030257

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The Gene Ontology (GO) term and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis for key genes from the blue module. The significant terms and pathways are represented by the negative decadic logarithm of the enrichment adjusted p-value (the longer bars indicate more significant clusters). (a,b) The GO analysis was done in blue modules; bar-plots and bubble-plots are drawn to show the top terms in groups of biological process (BP), cellular component (CC), and molecular function (MF). (c,d) The top terms of the KEGG pathway analysis for genes in the blue module are shown by bar-plot and bubble-plot also. (e) The cell cycle pathway (KEGG: hsa04110) was performed by DAVID (URL: https://david.ncifcrf.gov/tools.jsp), and key genes are marked in red.