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. 2020 Feb 29;11(3):268. doi: 10.3390/genes11030268

Table 1.

SNP effect concordance analysis (SECA) results for the test of genetic concordance between endometriosis and migraine.

P1 P2 Concordant SNPs Discordant SNPs Total SNPs Proportion of Concordance OR P
1 1 30790 28398 59188 0.52 1.18 8.77 × 10−23
0.9 0.9 27540 25213 52753 0.52 1.19 4.11 × 10−24
0.8 0.8 24222 21971 46193 0.52 1.22 1.30 × 10−25
0.7 0.7 20842 18665 39507 0.53 1.25 6.60 × 10−28
0.6 0.6 17474 15458 32932 0.53 1.28 1.23 × 10−28
0.5 0.5 14218 12383 26601 0.53 1.32 2.69 × 10−29
0.4 0.4 10973 9415 20388 0.54 1.36 1.31 × 10−27
0.3 0.3 7804 6510 14314 0.55 1.44 3.21 × 10−27
0.2 0.2 4771 3855 8626 0.55 1.53 6.92 × 10−23
0.1 0.1 1946 1496 3442 0.57 1.69 2.06 × 10−14
0.05 0.05 804 579 1383 0.58 1.92 2.23 × 10−09
0.01 0.01 85 43 128 0.66 3.61 7.20 × 10−04

P1: International Endogene Consortium (IEC) Endometriosis data p-value; P2: International Headache Genetics Consortium (IHGC) migraine data p-value; SNP: single nucleotide polymorphism; OR: odds ratio for the effect direction concordance association test for endometriosis and migraine; P: Fisher’s exact p-value for the effect direction concordance association test between endometriosis and migraine.