TABLE 2.
The contributions of different modalities.
| Modalities | ACC | SEN | SPE | BACC | AUC |
| MRI | 74.5 ± 0.4% | 54.8 ± 0.9% | 85.0 ± 0.3% | 69.9 ± 0.5% | 79.2 ± 0.2% |
| FDG-PET | 76.7 ± 0.4% | 55.1 ± 0.8% | 88.2 ± 0.5% | 71.7 ± 0.4% | 80.9 ± 0.2% |
| CSF | 73.0 ± 0.5% | 62.5 ± 1.0% | 78.7 ± 0.5% | 70.6 ± 0.6% | 79.0 ± 0.3% |
| CSF + APOEϵ4 | 73.9 ± 0.4% | 63.2 ± 0.7% | 79.7 ± 0.6% | 71.4 ± 0.4% | 78.8 ± 0.3% |
| - MRI | 81.3 ± 0.5% | 67.0 ± 1.0% | 89.0 ± 0.5% | 78.0 ± 0.6% | 86.8 ± 0.2% |
| - FDG-PET | 81.0 ± 0.5% | 67.2 ± 0.8% | 88.4 ± 0.5% | 77.8 ± 0.5% | 86.7 ± 0.2% |
| - CSF | 79.6 ± 0.6% | 63.5 ± 1.2% | 88.3 ± 0.5% | 75.9 ± 0.7% | 85.8 ± 0.2% |
| - APOEϵ4 | 83.2 ± 0.5% | 69.8 ± 1.0% | 90.4 ± 0.5% | 80.1 ± 0.6% | 88.7 ± 0.2% |
| - LASSO | 83.5 ± 0.6% | 69.0 ± 1.2% | 91.2 ± 0.6% | 80.1 ± 0.7% | 88.8 ± 0.2% |
| All | 84.7 ± 0.4% | 72.7 ± 0.8% | 91.2 ± 0.4% | 81.9 ± 0.5% | 88.8 ± 0.2% |
“- modality” means the absence of the modality in experiments. In each cell, the two numbers represent the mean and standard deviation derived from 100 runs of validation. ACC, accuracy; APOE, apolipoprotein E; AUC, area under receiver operating characteristic curve; BACC, balanced accuracy; CSF, cerebrospinal fluid; LASSO, least absolute shrinkage and selection operator; SEN, sensitivity; SPE, specificity.