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. Author manuscript; available in PMC: 2020 Jun 13.
Published in final edited form as: Science. 2019 Dec 13;366(6471):eaav1282. doi: 10.1126/science.aav1282

Fig. 4. Genetic depletion of metabolites in vivo by colonization with WT versus mutant strains of C. sporogenes.

Fig. 4.

Germ-free mice were monocolonized with WT C. sporogenes or the ΔcutC, ΔprdR, ΔporAhadB, ΔhadB, or ΔcroA mutants (n ≥ 5 mice per group). Metabolite levels were altered in the host by mutation of the corresponding pathway. Error bars indicate standard deviation. *P < 0.05, **P < 0.01, and ns is not significant.