Comparison 3. Subgroup analysis ‐ Type of CSF (G‐CSF vs. GM‐CSF).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
3.1 Patients with hospitalization for greater than 10 days	7	1087	Risk Ratio (M‐H, Random, 95% CI)	0.65 [0.44, 0.95]
3.1.1 G‐CSF	5	868	Risk Ratio (M‐H, Random, 95% CI)	0.79 [0.51, 1.23]
3.1.2 GM‐CSF	3	219	Risk Ratio (M‐H, Random, 95% CI)	0.40 [0.18, 0.92]
3.2 Time to neutrophil recovery	5	794	Risk Ratio (M‐H, Random, 95% CI)	0.52 [0.34, 0.81]
3.2.1 G‐CSF	4	665	Risk Ratio (M‐H, Random, 95% CI)	0.54 [0.31, 0.94]
3.2.2 GM‐CSF	2	129	Risk Ratio (M‐H, Random, 95% CI)	0.28 [0.04, 2.21]
3.3 Duration of grade IV neutropenia	9	1135	Std. Mean Difference (IV, Random, 95% CI)	‐1.70 [‐2.65, ‐0.76]
3.3.1 G‐CSF	5	784	Std. Mean Difference (IV, Random, 95% CI)	‐2.73 [‐4.43, ‐1.04]
3.3.2 GM‐CSF	5	351	Std. Mean Difference (IV, Random, 95% CI)	‐0.67 [‐1.12, ‐0.22]
3.4 Time to recovering from fever	9	966	Std. Mean Difference (IV, Random, 95% CI)	‐0.49 [‐0.90, ‐0.09]
3.4.1 G‐CSF	5	621	Std. Mean Difference (IV, Random, 95% CI)	‐0.78 [‐1.47, ‐0.08]
3.4.2 GM‐CSF	5	345	Std. Mean Difference (IV, Random, 95% CI)	‐0.20 [‐0.58, 0.18]
3.5 Time to withdrawal from antibiotics	3	457	Std. Mean Difference (IV, Random, 95% CI)	‐1.50 [‐2.83, ‐0.18]
3.5.1 G‐CSF	2	389	Std. Mean Difference (IV, Random, 95% CI)	‐1.86 [‐3.80, 0.07]
3.5.2 GM‐CSF	1	68	Std. Mean Difference (IV, Random, 95% CI)	‐0.77 [‐1.27, ‐0.28]