Random Genetic Epidemiology Research on Adult Health and Aging (GERA) patients. Average number of days of inhaled corticosteroids (ICS)–long-acting beta agonists (LABAs) is shown. Each patient is represented by a horizontal track, with a solid line indicating ICS–LABA coverage, and discrete events and prescription fills represented by shapes. Open shapes represent exacerbations: black circles are oral steroid bursts, diamonds are asthma-related hospitalizations, open squares are asthma-related emergency department visits. Colored stars represent prescription fills for a controller medication, with a horizontal line of the same color indicating the duration of that prescription. Chronic oral corticosteroids (OCS) are treated as a controller medication and represented by pink circles. The solid blue line indicates the percentage coverage of ICS–LABA, with a low line indicating 0% coverage, and a high line indicating 100% coverage. We averaged the duration of each ICS–LABA prescription over 180 days to quantify the uncertainty of adherence to ICS–LABAs.