Table 2.
ROC analysis for five annotated metabolites and five donor clinical parameters at pre-transplant for the prediction of EGF.
| Indicators | AUC | Accuracy | Sensitivity | Specificity |
|---|---|---|---|---|
| adenine/urate + AMP/urate + hypoxanthine/urate + ALT | 0.84 | 0.68 | 0.65 | 0.80 |
| adenine/urate + adenosine/urate + AMP/urate + hypoxanthine/urate | 0.80 | 0.70 | 0.65 | 0.90 |
| AMP/urate | 0.75 | 0.66 | 0.62 | 0.80 |
| GGT + bilirubin + AST + ALT + age + steatosis status | 0.71 | 0.57 | 0.57 | 0.60 |
| adenine/urate | 0.70 | 0.64 | 0.60 | 0.80 |
| hypoxanthine/urate | 0.68 | 0.53 | 0.51 | 0.60 |
| bilirubin | 0.65 | 0.68 | 0.67 | 0.70 |
| AST | 0.63 | 0.51 | 0.50 | 0.70 |
| adenosine/urate | 0.62 | 0.53 | 0.49 | 0.70 |
| ALT | 0.59 | 0.36 | 0.27 | 0.70 |
| steatosis status | 0.55 | 0.49 | 0.46 | 0.60 |
| age | 0.55 | 0.45 | 0.38 | 0.70 |
| GGT | 0.47 | 0.79 | 1 | 0 |
ROC, receiver operating characteristic; AUC, area under the curve; AMP, adenosine monophosphate.