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. 2020 Mar 6;9(3):715. doi: 10.3390/jcm9030715

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Titers of IgG-antibodies against the Negative Elongation Factor E across different diseases in two different cohorts: (A) initial derivation cohort including patients with sarcoidosis, systemic lupus erythematosus (SLE), febrile infectious disease (FID), patients with miscellaneous diseases within the positron emission tomography (PET)-controls and blood donors (BD); (B) validation cohort including patients with sarcoidosis (n = 58) and healthy controls (HC) (n = 13). The titer is considered positive, if it is the same or higher than the cut-off serum (dashed line. Global Kruskal-Wallis is shown, as well as pairwise Wilcoxon-tests of disease groups vs. the sarcoidosis group (**** indicates p < 0.0001; ** indicates p < 0.01, ns indicates p ≥ 0.05).