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. 2020 Mar 12;5(5):e134061. doi: 10.1172/jci.insight.134061

Figure 5. Tg21 mice had lower serum levels of ACTH, corticosterone, C-reactive protein, and Fgf21 but higher adiponectin levels during development of DIO.

Figure 5

(A–C) Serum levels of ACTH (A), corticosterone (B), and C-reactive protein (C) in age-matched (5 months) male Tg21 and WT mice during NCD or after 3 months of HFD feeding. (D and E) Serum levels of Fgf21 in male (D) and female (E) age-matched (5 months) Tg21 and WT mice during NCD or after 1 month or 3 months of HFD feeding. (F and G) Fat mass versus serum adiponectin levels in male (F) and female (G) age-matched (5 months) Tg21 and WT mice during NCD or after 3 months of HFD feeding. In box-and-whisker plots, bounds denote the 25th to 75th percentile, the lines represent the medians, and whiskers indicate the range from minimum to maximum values and includes outliers. *P < 0.05, **P < 0.01, ***P < 0.001 (2-way ANOVA), n = 6–8/group.