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. 2020 Mar 12;5(5):e132158. doi: 10.1172/jci.insight.132158

Figure 4. Hepatic free fatty acids, de novo lipogenesis, adipose tissue lipolysis, and hepatic insulin sensitivity are similar in carriers and noncarriers of the HSD17B13 rs72613567 variant.

Figure 4

(A) The concentrations of individual hepatic free fatty acids (TT, n = 48; TTA/TATA, n = 38) and (B) the rate of hepatic de novo lipogenesis (TT, n = 67; TTA/TATA, n = 59) in the HSD17B13 groups. (C) The rate of appearances of glycerol in the basal state and (D) during euglycemic hyperinsulinemia in the TT (n = 40) and TTA/TATA (n = 12) groups. (E) The rate of appearances of glucose in the basal state and (F) during euglycemic hyperinsulinemia in the TT (n = 62) and TTA/TATA (n = 43) groups. The data were analyzed using independent 2-sample Student’s t test and are shown as mean ± SEM. Black bars = TT; green bars = TTA/TATA. FFM, fat free mass.