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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Adv Biosyst. 2019 Oct 1;3(12):1900141. doi: 10.1002/adbi.201900141

Figure 3.

Figure 3.

BMP-2 is observable within MSC spheroids when adsorbed onto HA. (A) Schematic of BMP-2 adsorption onto HA and incorporation into spheroids. (B) Representative brightfield images with a fluorescence overlay of spheroids with BMP-2 (green) adsorbed onto HA, in culture media, or not present. Scale bar is 500 μm. (C) Quantification of the relative fluorescence intensity of spheroids treated with HA alone, HA with soluble BMP-2, or BMP-2 adsorbed onto HA (n=3). Groups with different letters are statistically different based on a one-way ANOVA with p<0.05. Data are mean ± standard deviation.