Effects of PostC, melatonin and Px administrations on irisin mRNA expression. (a) Significant difference when compared to control, (b) Significant difference due to postconditioning when compared to ischemia/reperfusion, (c) Significant difference due to application of melatonin when compared to ischemia/reperfusion, (e) Significant difference due to postconditioning and melatonin co-administration when compared to ischemia/reperfusion in pinealectomized rats (p<0.05)
I/R - ischemia/reperfusion, PostC - postconditioning, mel - melatonin (10 mg/kg), Px - pinealectomy, n=7