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. 2020 Mar 20;9(3):843. doi: 10.3390/jcm9030843

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effect of the 7-day high-salt (HS) diet without (HS group) and with vitamin C and E (HS+C+E group) supplementation on skin microvascular reactivity in young healthy individuals. (A) Post-occlusive reactive hyperemia (PORH), (B) Acetylcholine-induced dilation (AChID), and (C) Sodium nitroprusside induced dilation (SNPID). PORH measurement is expressed as the difference between percentage of flow change during reperfusion and occlusion in relation with baseline (R-O%). AChID and SNPID are expressed as flow increase following ACh or SNP administration compared to baseline flow. Data are presented as average ± SD. LS- low-salt; HS- high-salt; HS+C+E- high-salt + C vitamin + E vitamin; R-O%- change of microvascular blood flow between reperfusion and occlusion (in relation to baseline); AChID- acetylcholine induced dilation; SNPID- sodium nitroprusside induced dilation. *p < 0.05, LS diet vs. HS diet within the HS group. † p < 0.05 HS diet vs. HS+C+E diet.

The effect of the 7-day high-salt (HS) diet without (HS group) and with vitamin C and E (HS+C+E group) supplementation on skin microvascular reactivity in young healthy individuals. (A) Post-occlusive reactive hyperemia (PORH), (B) Acetylcholine-induced dilation (AChID), and (C) Sodium nitroprusside induced dilation (SNPID). PORH measurement is expressed as the difference between percentage of flow change during reperfusion and occlusion in relation with baseline (R-O%). AChID and SNPID are expressed as flow increase following ACh or SNP administration compared to baseline flow. Data are presented as average ± SD. LS- low-salt; HS- high-salt; HS+C+E- high-salt + C vitamin + E vitamin; R-O%- change of microvascular blood flow between reperfusion and occlusion (in relation to baseline); AChID- acetylcholine induced dilation; SNPID- sodium nitroprusside induced dilation. *p < 0.05, LS diet vs. HS diet within the HS group. † p < 0.05 HS diet vs. HS+C+E diet.