Choleraa
|
Ganges delta, 5 KYA |
Vibrio cholerae |
NF-κB, cAMP-mediated chloride secretion blood group |
Leprosyb
|
Sub-Sahara, >10 KYA |
Mycobacterium leprae |
TLR1 gene, CYLD
|
Nematodesc,d
|
Ancient Europe-Western Asia |
Soil and meat-borne: whipworm Ascaris; roundworm Trichuris
|
ApoE4 |
Plaguee
|
Eurasia, 5–3.5 KYA |
Yersinia pestis, modern; many candidate pathogens |
CCRΔ32 |
Small poxb
|
Africa, 15–70 KYA |
Variola virus |
CCRΔ32 |
Gonorrhea |
Africa, >100 KYA |
Neisseria gonorrhoeae |
Siglec-16g
|
Malariab
|
Africa, >100 KYA |
Plasmodium falciparum |
Duffy, G6PD deficiency, α+ thalassemia, hemoglobin C, CGYPA/B/C-deficient erythrocytes |
Malariaf
|
Africa, 22 KYA |
P. falciparum |
Hemoglobin βS, sickle cell mutant |