Table 2. Global design of the study.
| SRX | SRS | ||
|---|---|---|---|
| Exposure | Acute | acute | repeated |
| Emission duration | 10 s every 5 min for 1 h | 2 x 8 min with 10 min interval Avoidance: 14 min continuous | 2 x 8 min with 10 min interval 5 days/week for 8 weeks |
| Age at experiment | 6 weeks | 6 weeks | 6 weeks |
| N animals/exposition | 1 | 1 | 12 |
| Behavioural tests | Beam walking (n = 13/11a), rotarod (n = 12/12), T-maze (13/11), open field (n = 12/12), avoidance (n = 11/10) | Beam walking, rotarod, T-maze, avoidance (n = 12/12) | T-maze (n = 8/8, wk14b), Beam walking (n = 12/12, wk15), rotarod (n = 24/24, wk16) |
| GFAP staining (J = exposition day n = nb animals) | J+2n = 12/12 J+7 n = 11/11 | J+2 n = 12/12 | |
| Anatomo-pathology (HES) | 104 weeks or at death | 104 weeks or at death | 104 weeks or at death |
| Lifespan recording (up to 2 years) | n = 24/24 | ||
an = n1/n2 = [number of exposed animals] / [number of sham animals].
bwk = age of animals at the date of test.