Figure 2.

Clinical course of OS MM patient showing FLC ratio, diagnostic and immunophenotypic images. A, Axial sequence TSE T2‐weighted abdominal MRI scan with multiple focal and bilobar lesions, confirmed with echo‐guided mass biopsy as EMD relapse. B, Dot plot shows the presence of plasma cells CD38 + CD138+, evaluated in cytometry, in extramedullary site. C, FLC curve in OS MM patient with hepatic EMD relapse following progressive FLC alteration (OSMM—oligo‐secretory multiple myeloma; FLC I/U ratio—free light chain involved/uninvolved ratio (n.v. 0.31‐1.56); MC—monoclonal component; KRd—carfilzomib, lenalidomide, dexamethasone; EMD—extramedullary myeloma disease)