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Morphologic resemblance among high-grade pancreatic neuroendocrine neoplasms. A through C, Well-differentiated pancreatic neuroendocrine tumor (PanNET), grade 3. B, Ki-67 more than 20% classifies this PanNET into grade 3. D, Poorly differentiated pancreatic neuroendocrine carcinoma (PanNEC), large cell carcinoma. E, Poorly differentiated PanNEC, small cell carcinoma (hematoxylin-eosin, original magnification ×200 [A, C, D, and E]; original magnification ×100 [B]).
