Table 4. Risk factors in a multivariate logistic regression model for AKD in patients on ECMO.
| Crude | Adjusted* | |||
|---|---|---|---|---|
| Variables | OR (95% CI) | p-value | OR (95% CI) | p-value |
| Age (years) | 1.024 (1.004–1.045) | 0.018 | 1.027 (0.997–1.058) | 0.158 |
| Male gender | 1.552 (0.805–2.990) | 0.189 | 1.107 (0.487–2.518) | 0.808 |
| Duration of ECMO support (days) | 1.040 (1.002–1.079) | 0.037 | 1.039(0.995–1.084) | 0.082 |
| APACHE II score on day 1 of ECMO | 1.055 (1.015–1.097) | 0.007 | 1.001 (0.928–1.081) | 0.972 |
| SOFA score on day 1 of ECMO | 1.091 (1.007–1.181) | 0.033 | 0.962 (0.837–1.106) | 0.59 |
| GCS score on day 1 of ECMO | 0.915 (0.852–0.982) | 0.014 | 0.87 (0.761–1.002) | 0.077 |
| MAP on day 1 of ECMO (mmHg) | 0.977 (0.959–0.997) | 0.022 | 0.979 (0.956–1.003) | 0.083 |
| UO on day 1 of ECMO (100mL) | 0.967 (0.945–0.990) | 0.005 | 0.969 (0.941–0.997) | 0.033 |
| K+ concentration on day 1 of ECMO (mEq/L) | 1.390 (1.047–1.845) | 0.023 | 1.482 (1.015–2.163) | 0.042 |
| Baseline eGFR | 1.001 (0.991–1.011) | 0.826 | 1.010 (0.996–1.023) | 0.153 |
| AKI | 2.623 (1.26–5.462) | 0.01 | 2.257 (0.781–6.518) | 0.133 |
Abbreviation: ECMO, extracorporeal membrane oxygenation; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment; GCS, Glasgow Coma Scale; MAP, mean arterial pressure; UO, urine output; eGFR, estimated glomerular filtration rate
*Adjusted for age, sex, duration of ECMO support, APACHE II score, SOFA score, GCS score, MAP, urine output, serum potassium concentration, and baseline eGFR.