Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The mismatch-aware guide matching strategy. Characters are encoded using four-bit notation, as illustrated in the table on the left. For a given genomic position, this step compares the characters of the guide with the characters of the genome using bitwise operations. In the example the guide matching starts from index 24
