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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: J Immunol. 2020 Mar 9;204(8):2192–2202. doi: 10.4049/jimmunol.1900912

FIGURE 2.

FIGURE 2.

Type I IFN production induced in response to B. pertussis infection in adult mice. Mice (n ≥ 4 per group) were euthanized on the indicated dpi (x-axis) with B. pertussis or PBS sham inoculum, and lungs were dissected for assessment of (A) bacterial burdens by plating for viable counts, (B and C) mRNA levels of IFN-α and IFN-β by quantitative RT-PCR, or (D and E) IFN-α and IFN-β protein levels by ELISA. Data are representative of at least two independent experiments. *p < 0.05, ***p < 0.001 by the Student t test and two-way ANOVA.