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. 2020 Mar 2;39(15):3195–3205. doi: 10.1038/s41388-020-1209-4

Fig. 1. ZBTB7A promotes granulopoiesis while blocking monocytic differentiation.

Fig. 1

a HL60 cells stably expressing an empty vector (EV), ZBTB7A WT or mutants were differentiated by ATRA treatment. CD11b expression was assessed by flow cytometry. b HL60 cells stably expressing ZBTB7A WT or mutants were differentiated by PMA treatment. CD14 expression was assessed by flow cytometry. c HL60 ZBTB7A KO and HL60 ZBTB7A KO stably expressing ZBTB7A WT or mutants without induction of differentiation. CD14 expression was assessed by flow cytometry. d Competitive growth of HL60 cells stably expressing ZBTB7A WT or mutants. e Western blot from K562 cells, arrow indicates low levels of the ZBTB7A A175fs mutant. f K562 ZBTB7A KO without induction of differentiation. CD235a expression was assessed by flow cytometry. *p value < 0.05 compared with control cells.