Table 3.
Multivariate analysis of factors to predict progression-free and overall of apatinib. PFS, progression-free survival; OS, overall survival; NLR, neutrophil/lymphocyte ratio; CA19–9, carbohydrate antigen 19–9; HR, hazard ratios.
| Variables | PFS | OS | ||
|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | |
| NLR | ||||
| <4.1/≥4.1 | 0.222 (0.053–0.935) | 0.040 | 0.347 (0.172–0.702) | 0.003 |
| CA19–9 decrease | ||||
| No/yes | 11.807 (1.771–78.708) | 0.011 | 1.972 (0.909–4.278) | 0.086 |
| Hand-foot syndrome | ||||
| No/yes | 1.119 (0.165–7.737) | 0.909 | 1.164 (0.516–2.625) | 0.715 |