Table 1.
Correlation between expression of ZNF703 protein and clinicopathological characteristics in HCC patients (n = 128).
| Variables | ZNF703 | |||
|---|---|---|---|---|
| n | negative expression | positive expression | P Value | |
| Gender | ||||
| Male | 108 | 48 | 60 | |
| Female | 20 | 8 | 12 | 0.713 |
| Age (years) | ||||
| ≤50 | 54 | 24 | 30 | |
| >50 | 74 | 32 | 42 | 0.892 |
| HBsAg | ||||
| Positive | 102 | 44 | 58 | |
| Negative | 26 | 12 | 14 | 0.782 |
| Serum AFP | ||||
| ≤20 ng/ml | 28 | 11 | 17 | |
| >20 ng/ml | 100 | 45 | 55 | 0.590 |
| Cirrhosis | ||||
| Yes | 110 | 46 | 64 | |
| No | 18 | 10 | 8 | 0.276 |
| Differentiation | ||||
| Well-moderate | 98 | 48 | 50 | |
| Poor-undifferentiated | 30 | 8 | 22 | 0.031 |
| Tumor size | ||||
| ≤5 cm | 27 | 7 | 20 | |
| >5 cm | 101 | 49 | 52 | 0.036 |
| Tumor number | ||||
| Single | 69 | 35 | 34 | |
| Multiple | 59 | 21 | 38 | 0.085 |
| Tumor encapsulation | ||||
| Absent | 72 | 35 | 37 | |
| Present | 56 | 21 | 35 | 0.209 |
| Vascular invasion | ||||
| Yes | 25 | 5 | 20 | |
| No | 103 | 51 | 52 | 0.008 |
| LNM | ||||
| Yes | 23 | 5 | 18 | |
| No | 105 | 51 | 54 | 0.019 |
| TNM | ||||
| I~II | 73 | 38 | 35 | |
| III~IV | 55 | 18 | 37 | 0.029 |
AFP alpha-fetoprotein, LNM lymph node metastasis, HBsAg hepatitis B surface antigen.
P values by Chi-square test.
Bold values indicate statistical significance, P < 0.05.