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. 2020 Apr 8;10:6096. doi: 10.1038/s41598-020-63276-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of tumor-associated macrophage (TAM) polarization. (A) M1 and M2 percentages and the M1/M2 ratio among TAMs isolated from primary high-grade serous ovarian cancer, different ovarian cancer histotypes and ovarian metastases from other sites. (B) Intracellular content of heme in TAMs isolated from patients with primary high-grade serous ovarian cancer, TAMs isolated from patients with different ovarian cancer histotypes, and patients with ovarian metastases from other sites.