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. 2020 Apr 8;10:6096. doi: 10.1038/s41598-020-63276-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation of tumor-associated macrophage (TAM) polarization with patient prognosis. (A) Regression analysis of the M1/M2 ratio and progression-free survival and overall survival in the entire cohort of patients and in patient subgroups based on tumor histotypes and the extent of surgery. (B) The M1/M2 ratio among TAMS isolated from primary high-grade serous ovarian cancer patients stratified based on platinum sensitivity. (C) Correlation analysis between the M1/M2 ratio and progression-free survival, overall survival and platinum sensitivity in patients with primary high-grade serous ovarian cancer stratified based on the extent of surgery.