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. 2020 Apr 8;10:6057. doi: 10.1038/s41598-020-63046-z

Table 3.

Characteristics of ISSNHL based on hearing levels (n = 759 ears, n (%)).

Characteristics Mild Moderate Moderate to severe Severe Profound Z P
(n = 101) (n = 103) (n = 123) (n = 179) (n = 253)
Male 43 (42.6) 56 (54.4) 66 (53.7) 110 (61.5) 128 (50.6) −0.708 0.479
Female 58 (57.4) 47 (45.6) 57 (46.3) 69 (38.5) 125 (49.4)
Unilateral hearing loss 96 (95.0) 91 (88.3) 115 (93.5) 173 (96.6) 244 (96.4) −2.125 0.034
Bilateral hearing loss 5 (5.0) 12 (11.7) 8 (6.5) 6 (3.4) 9 (3.6)
Accompanying symptoms
Tinnitus 98 (97.0) 101 (98.1) 120 (97.6) 175 (97.8) 242 (95.7) −1.143 0.253
Vertigo 7 (6.9) 7 (6.8) 8 (6.5) 20 (11.2) 48 (19.0) −4.266 0.000
BPPV 1 (1.0) 1 (1.0) 3 (2.4) 5 (2.8) 10 (4.0) −1.936 0.053
comorbidities
Hypertension 16 (15.8) 28 (27.2) 20 (16.3) 41 (22.9) 69 (27.3) −2.06 0.039
Diabetes 0 (0) 4 (3.9) 5 (4.1) 16 (8.9) 17 (6.7) −2.55 0.011
Abnormal blood coagulation
High fibrinogen 1 (1.0) 4 (3.9) 3 (2.4) 6 (3.4) 11 (4.3) −1.364 0.173
Reduced APTT 3 (3.0) 5 (4.9) 5 (4.1) 11 (6.1) 19 (7.5) −1.862 0.063
Reduced PT 2 (2.0) 6 (5.8) 1 (0.8) 1 (0.6) 5 (2.0) −1.02 0.308
High blood lipid
High TC 37 (36.6) 39 (37.9) 45 (36.6) 71 (39.7) 92 (36.4) −0.089 0.929
High TG 14 (13.9) 16 (15.5) 18 (14.6) 36 (20.1) 60 (23.7) −2.709 0.007
Low HDL 31 (30.7) 45 (43.7) 50 (40.7) 69 (38.5) 113 (44.7) −1.748 0.081
High LDL 44 (43.6) 47 (45.6) 53 (43.1) 81 (45.3) 100 (39.5) −0.997 0.319

Data were analyzed by non-parametric Mann-Whitney U test.