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The top 10 type and frequency of GBPs neighbor gene alterations in HNSCC (cBioPortal).
| Gene Symbol | Amplification | Up-regulation | Down-regulation | Mutation | Total Alteration |
|---|---|---|---|---|---|
| ADAR | 1.3 | 6.2 | 0.4 | 1.5 | 9.1 |
| IRF6 | 0.9 | 6.6 | 0.4 | 0.9 | 8.7 |
| IRF9 | 0.6 | 6.0 | 1.5 | 0.4 | 8.7 |
| IRF2 | 0.4 | 2.1 | 2.8 | 1.5 | 8.4 |
| CD44 | 3.4 | 6.6 | 0.4 | 0.6 | 8.5 |
| STAT1 | 2.8 | 4.9 | 0 | 2.8 | 8.5 |
| FCGR1A | 2.1 | 4.2 | 0 | 0.2 | 7.9 |
| NFATC2 | 0.2 | 4.3 | 0 | 2.8 | 7.5 |
| ICAM1 | 0.9 | 4.0 | 0 | 1.1 | 7.0 |
| STAT2 | 0.4 | 5.1 | 0 | 0.9 | 6.4 |
