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. 2020 Apr 8;11(4):227. doi: 10.1038/s41419-020-2416-1

Fig. 8. Structure chart of the role of the HOTAIRM1/miR-107/TDG axis in PTC progression.

Fig. 8

Our combined data indicated a model whereby HOTAIRM1 inhibited PTC cell proliferation and invasion through sponging miR-107 to decrease the expression of TDG, a key DNA repair and replication proteins associated with critical aspects of cellular function.