Fig. 2. FMDS ¹¹C-carboxylation with sp-hybridized carbon attached trimethylsilanes.

Unless otherwise indicated, the reported values are radiochemical yields (RCY, n = 3) of determined by radio-HPLC analysis of the crude product and the product identities were determined by co-injection with corresponding carbon-12 standards. ^aTHF (0.5 mL) + DMF (0.25 mL) were used; ^bReaction was maintained at r.t., 2 min; ^cDMSO was used as solvent; ^dPrecursor (0.029 mmol, 5 mg) and DMF (0.3 mL) were used for reactions.