Table 3. List of biological pathways affected by phenylalanine or valine treatment.

Detected pathway	Phenylalanine	Valine
Alzheimer disease-presenilin pathway	•1)	•
Angiogenesis	•
Apoptosis signaling pathway		•
ATP synthesis	•	•
Cadherin signaling pathway	•	•
Cholecystokinin receptor signaling map	•	•
Cytoskeletal regulation by Rho GTPase	•	•
De novo purine biosynthesis	•	•
De novo pyrimidine deoxyribonucleotide biosynthesis	•	•
De novo pyrimidine ribonucleotides biosynthesis	•	•
Dopamine receptor mediated signaling pathway	•
Epidermal growth factor receptor signaling pathway	•	•
Fibroblast growth factor signaling pathway	•	•
Fructose galactose metabolism		•
Glycolysis	•	•
Gonadotropin-releasing hormone receptor pathway	•	•
Huntington disease	•	•
Integrin signaling pathway	•	•
Nicotine pharmacodynamics pathway	•
p38 mitogen-activated protein kinase pathway	•
p53 pathway	•	•
Parkinson disease	•	•
Pentose phosphate pathway	•
PI3 kinase pathway		•
Salvage pyrimidine ribonucleotides	•	•
Vascular endothelial growth factor signaling pathway	•
Wnt signaling pathway	•	•

Pathway analysis was performed using PANTHER (http://www.pantherdb.org).

¹⁾Affected pathways after phenylalanine or valine treatment.