Table 3.
Change in biochemical/clinical parameters and SWV values at baseline and after 9-month treatment with Saroglitazar 4 mg once daily.
| Baseline | 9 months | Change from baseline | P value | |
|---|---|---|---|---|
| Waist circumference (inches) | 37.6 ± 3.138 | 37.51 ± 3.123 | −0.09 | 0.54 |
| BMI (kg/m2) | 25.21 ± 3.07 | 24.81 ± 2.95 | −0.4 | 0.046 |
| FBG (mg/dL) | 139.5 ± 15.67 | 106.5 ± 14.94 | −33 | <0.0001 |
| HbA1c (%) | 7.8 ± 0.343 | 6.9 ± 0.33 | −0.9 | <0.0001 |
| TG (mg/dL) | 298.2 ± 35.75 | 202.4 ± 13.19 | −95.8 | <0.0001 |
| HDL-C (mg/dL) | 40.79 ± 5.63 | 45.2 ± 4.36 | 4.4 | 0.0007 |
| ALT (U/L) | 64.7 ± 15.56 | 46.2 ± 12.6 | −18.5 | 0.0058 |
| AST (U/L) | 43.4 ± 10.48 | 35.4 ± 6.59 | −8 | 0.0321 |
| SWV (M/S) | 1.837 ± 0.0691 | 1.645 ± 0.0844 | −0.192 | 0.0004 |
| SBP (mmHg) | 136 ± 6.04 | 134.6 ± 7.24 | −1.4 | 0.0445 |
n = 10; data are mean ± SD; paired “t” test.