Table 1.
Characteristics | Patient 1 | Patient 2 | Patient 3 |
---|---|---|---|
Gender | Female | Male | Male |
Age (years) | 72 | 49 | 66 |
BMI (kg/m2) | 13.4 | 17.2 | 21.4 |
Underlying diseases | Hypertension; bronchiectasis | Tuberculosis; bronchiectasis; drug-induced liver injury | Hypertension; bronchiectasis; diabetes mellitus |
Symptoms | Cough; sputum | Cough; sputum; emaciation | Cough; sputum; chest tightness; hemoptysis |
Radiographic characteristics | Bilateral involvement; bronchiectasis, multiple thin wall cavities | Bilateral involvement; bronchiectasis; multiple cavities | Bilateral involvement; bronchiectasis; multiple cavities; pleural effusion |
Initial AFB positive | Yes | Yes | Yes |
Antibiotics useda | H, Rft, E, Clr, Imi, Lzd, Lfx | Cfz, Rfb, Au, Pa, Cm, M, Clr | H, Rft, E, Clr, Lzd, Ami, Tgc, Lfx |
Duration of treatment | 7 months | 28 months | 19 months |
Radiological result | No change | Progressed | Progressed |
Sputum conversion | Withdrawn | Persistent positive sputum culture with TB and M. abscessus | Relapse after conversion to negative |
aH, isoniazid; Rft, rifapentine; E, ethambutol; Clr, clarithromycin; Lzd, linezolid; Imi, imipenem; Lfx, levofloxacin; Ami, amikacin; Tgc, tigecycline; Rfb, rifabutin; Cfz, clofazimine; Pa, dipasic; M, moxifloxacin; Cm, capreomycin; Au, amoxicillin/clavulanate.