Table 3. Logistic Regression Analyses Predicting Pharmacotherapy From the Original and Simplified Finnegan Neonatal Abstinence Scoring Tool Items Among 424 Neonates.
| Original binary item | Univariate analysisa | Simplified model with 8 items a,b | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| High-pitched crying | 4.1 (2.0-8.1) | <.001 | NA | NA |
| Sleeps <3 h after feeding | 3.1 (1.9-5.0) | <.001 | 2.8 (1.6-4.8) | <.001 |
| Hyperactive Moro reflex | 3.5 (2.0-6.2) | <.001 | NA | NA |
| Tremors | ||||
| When disturbed | 2.3 (1.3-3.9) | .003 | 4.6 (2.0-10.2) | <.001 |
| When undisturbed | 5.0 (2.9-8.7) | <.001 | ||
| Increased muscle tone | 10.0 (3.9-26.0) | <.001 | 9.1 (3.0-27.8) | <.001 |
| Excoriation | 2.1 (1.2-3.5) | .007 | NA | NA |
| Myoclonic jerks | 7.1 (0.9-57.4) | .07 | NA | NA |
| Generalized convulsions | NA | NA | NA | NA |
| Sweating | 5.2 (1.5-18.1) | .01 | NA | NA |
| Body temperature ≥37.2 °C | 2.1 (1.3-3.5) | .002 | 1.9 (1.1-3.3) | .0318 |
| Yawning >3 times/scoring interval | 1.4 (0.5-3.7) | .48 | NA | NA |
| Mottling | 1.4 (0.8-2.3) | .19 | NA | NA |
| Nasal stuffiness | 1.5 (0.8-2.9) | .25 | NA | NA |
| Sneezing >3 times/scoring interval | 1.8 (1.1-2.8) | .01 | NA | NA |
| Nasal flaring | 2.2 (0.7-7.2) | .19 | NA | NA |
| Respiratory rate >60/min | 2.6 (1.6-4.1) | <.001 | 2.0 (1.1-3.4) | .01 |
| Excessive sucking | 2.4 (1.5-3.8) | <.001 | 2.0 (1.2-3.5) | .01 |
| Poor feeding | 3.0 (1.7-5.3) | <.001 | 2.7 (1.4-5.3) | .004 |
| Regurgitation | 3.2 (1.7-6.2) | <.001 | 4.0 (1.8-8.8) | <.001 |
| Loose or watery stools | 1.5 (0.9-2.5) | .13 | NA | NA |
Abbreviations: NA, not applicable; OR, odds ratio.
a
All models adjusted for cohort.
b
Area under the curve for simplified model was 0.86 (95% CI, 0.82-0.89). Cells marked with NA indicate that the original binary item was not retained in the simplified Finnegan Neonatal Abstinence Scoring Tool.