Table 1.
Characteristics of the EC patients grouped by the radiotherapy technique.
| Characteristic | IMRT (n = 138) | 3D-CRT (n = 293) | p value |
|---|---|---|---|
| Gender | 0.094 | ||
| Male | 128 (92.8%) | 256 (87.4%) | |
| Female | 10 (7.2%) | 37 (12.6%) | |
|
| |||
| Age (years) | 0.209 | ||
| <55 | 36 (26.1%) | 63 (21.5%) | |
| 55∼65 | 56 (40.6%) | 107 (36.5%) | |
| 65∼75 | 34 (24.6%) | 76 (26.0%) | |
| ≥75 | 12 (8.7%) | 47 (16.0%) | |
|
| |||
| Type of medical insurance | 0.307 | ||
| None | 30 (21.7%) | 83 (28.3%) | |
| New rural cooperative medical insurance | 27 (19.6%) | 58 (19.8%) | |
| Urban employee or resident insurance | 81 (58.7%) | 152 (51.9%) | |
|
| |||
| Smoking status | 0.078 | ||
| No | 26 (18.9%) | 78 (26.6%) | |
| Yes | 112 (81.1%) | 215 (73.4%) | |
|
| |||
| Smoking intensity (cig/d) | 0.331 | ||
| 1∼10 | 5 (4.5%) | 22 (10.2%) | |
| 11∼20 | 25 (22.3%) | 41 (19.1%) | |
| 21∼40 | 69 (61.6%) | 128 (59.4%) | |
| >40 | 13 (11.6%) | 24 (11.3%) | |
|
| |||
| Smoking duration (years) | 0.331 | ||
| <20 | 3 (2.7%) | 13 (6.0%) | |
| 20∼40 | 72 (64.3%) | 126 (58.6%) | |
| ≧40 | 37 (33.0%) | 76 (35.4%) | |
|
| |||
| Quit smoking | 0.013 | ||
| No | 100 (89.3%) | 168 (78.1%) | |
| Yes | 12 (10.7%) | 47 (21.9%) | |
|
| |||
| Drinking status | 0.793 | ||
| No | 50 (36.2%) | 110 (37.5%) | |
| Yes | 88 (63.8%) | 183 (62.5%) | |
|
| |||
| Alcohol consumption | 0.314 | ||
| Low risk | 22 (25.0%) | 48 (26.2%) | |
| Medium risk | 11 (12.5%) | 23 (12.6%) | |
| High risk | 33 (37.5%) | 50 (27.3%) | |
| Very high risk | 22 (25.0%) | 62 (33.9%) | |
|
| |||
| Drinking duration (years) | 0.094 | ||
| <20 | 16 (18.2%) | 30 (16.4%) | |
| 20∼40 | 49 (55.7%) | 100 (54.6%) | |
| >40 | 23 (26.1%) | 53 (29.0%) | |
|
| |||
| Quit drinking | 0.326 | ||
| No | 75 (85.2%) | 147 (80.3%) | |
| Yes | 13 (14.8%) | 36 (19.7%) | |
|
| |||
| Weight loss (kg) | 0.183 | ||
| No | 10 (7.2%) | 29 (9.9%) | |
| <5 | 76 (55.1%) | 184 (62.8%) | |
| ≧5, <10 | 29 (21.0%) | 40 (13.6%) | |
| ≧10, <15 | 13 (9.5%) | 27 (9.2%) | |
| ≧15 | 10 (7.2%) | 13 (4.5%) | |
|
| |||
| Pathology | 0.121 | ||
| Squamous cell carcinoma | 120 (87.0%) | 229 (78.1%) | |
| Adenocarcinoma | 2 (1.4%) | 16 (5.5%) | |
| Adenosquamous carcinoma | 1 (0.7%) | 4 (1.4%) | |
| Small-cell carcinoma | 0 (0.0%) | 4 (1.4%) | |
| Unknown | 15 (10.9%) | 40 (13.6%) | |
|
| |||
| Chemotherapy | 0.0001 | ||
| No | 59 (42.8%) | 183 (62.5%) | |
| Yes | 79 (57.2%) | 110 (37.5%) | |
|
| |||
| Concurrent chemotherapy | 0.286 | ||
| 5-Fu + Platinum-based drugs | 55 (70.5%) | 68 (63.6%) | |
| Cisplatin | 8 (10.3%) | 20 (18.7%) | |
| Others | 15 (19.2%) | 19 (17.7%) | |
|
| |||
| Radiation dose (Gy) | 0.171 | ||
| <60 | 55 (39.9%) | 97 (33.1%) | |
| ≧60 | 83 (60.1%) | 196 (66.9%) | |
|
| |||
| Previous treatment | 0.004 | ||
| No | 75 (54.3%) | 201 (68.6%) | |
| Yes | 63 (45.7%) | 92 (31.4%) | |
|
| |||
| Previous treatment methods | 0.001 | ||
| Surgery | 36 (57.1%) | 67 (72.8%) | |
| Chemotherapy | 5 (7.9%) | 16 (17.4%) | |
| Radiation therapy | 16 (25.5%) | 8 (8.7%) | |
| Chemoradiotherapy | 6 (9.5%) | 1 (1.1%) | |
EC, esophageal cancer; IMRT, intensity-modulated radiation therapy; 3D-CRT, three-dimensional conformal radiation therapy; kg, kilogram; Gy, gray unit.