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ALP activity in mice calvaria defects implanted with PHB/BC scaffolds after 3 days, 4 weeks and 20 weeks post-implantation. ### p < 0.0001 scaffods vs negative control (calvaria defect) at 3 days; **** p < 0.0001 3 days vs. 4 weeks (for each scaffold) si **** p < 0.0001 3 days vs. 20 weeks (for each scaffold).
