Table 4.
Association between serum transaminase and liver fibrosis overestimation. Models were realized according to fibrosis measurement one-year after SVR12. VIF: variance inflation factor; AIC: Aikake information criterion; BIC: Bayesian information criterion; AUROC: area under the receiver-operating characteristic curve.
| Model 1 (M1) (Overestimation of One Fibrosis Stage) |
Model 2 (M2) (Overestimation of Two or More Fibrosis Stages) |
|||
|---|---|---|---|---|
| Model Parameters | M1-AST | M1-ALT | M2-AST | M2-ALT |
| Linear Predictor | −0.479 + 0.005×[AST] | −1.329 + 0.018×[ALT] | −5.525 + 0.056×[AST] | −11.497 + 0.127×[ALT] |
| VIF | 2.532 | 1.712 | ||
| AIC | 210 | 209 | 89 | 88 |
| BIC | 213 | 200 | 92 | 90 |
| AUROC | 0.623 (0.4;0.685) |
0.623 (0.485;0.761) |
0.936 (0.882;0.989) |
0.958 (0.922;0.996) |
| Nagelkerke-PseudoR2 | 0.009 | 0.088 | 0.682 | 0.785 |
| Hosmer-Lemeshow p-value | 0.048 | 0.025 | 0.203 | 0.96 |