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. 2020 Feb 26;8(3):324. doi: 10.3390/microorganisms8030324

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Median-joining (MJ) network of vacA s genotypes. The non-neoplastic gastro-duodenal lesions cluster to s1a, s1b, and s2, while the cases of gastric intraepithelial neoplasia (GIN), except GIN5 (Italy 5, an s1a/b recombinant), join cluster s1a. Dots representing gastric lesions are color-coded as follows: GINs, red; non-atrophic gastritis (NAG) alone, green; NAG plus gastric erosions, grey; NAG plus duodenal ulcer, yellow. Dot sizes reflect the number of cases sharing the same vacA s genotype.