Table 2. Sex-Adjusted and Fully Adjusted Hazard Ratios for Affective Case Accumulation and All-Cause Mortality^a.

No. of affective cases	Hazard ratio (95% CI)
	Sex adjusted	Sex-adjusted plus excluded external causes of deathb	Sex-adjusted plus excluded schizophrenia casesc	Fully adjustedd
0	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]
1	1.76 (1.29-2.38)	1.73 (1.26-2.39)	1.75 (1.29-2.38)	1.46 (1.06-2.02)
2	1.87 (1.18-2.97)	1.87 (1.17-2.97)	1.74 (1.08-2.81)	1.16 (0.72-1.89)
3-4	2.34 (1.36-4.04)	2.33 (1.32-4.10)	2.30 (1.31-4.03)	1.18 (0.62-2.25)

^aBased on 15 imputations and 235 deaths (n = 3001).

^bTotal of 2981 participants, 215 deaths.

^cTotal of 2984 participants, 231 deaths.

^dAdjusted for all covariates listed in Table 1.