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. 2020 Feb 15;17(1):132–141. doi: 10.20892/j.issn.2095-3941.2019.0224

Figure 3.

Figure 3

Prophylaxis studies on the antitumor effect of OCT4-3 + Toll-like receptor-9 (TLR9) in BABL/c mice. (A) Tumor growth curve of the BALB/c mice bearing an F9 cell xenograft. Compared with phosphate-buffered saline (PBS) and OCT4-3 + TLR9, significant reduction in tumor growth for OCT4-3 + TLR9 could be observed (*P < 0.05). (B) Scatter diagram of tumor weight. Measurement of subcutaneous tumor weight 25 days after inoculation in prophylactic settings (*P < 0.05). (C) Tumor images from each group following the removal of tumors from euthanized mice at the end of the study. (D) Overall survival curves of mice treated as mentioned with PBS, TLR9, OCT4-3, or OCT4-3 + TLR9. **P < 0.01 (log-rank test) vs. PBS groups.