Table 3.
Odds Ratio (OR) (95% Confidence Interval (CI)) for Hearing Loss by Relative Telomere Length (RTL) Levels through Conditional Logistic Regression.
| RTL Levels | Case/Control | Crude | Adjusted a |
|---|---|---|---|
| OR (95% CI) | OR (95% CI) | ||
| Per doubling of RTL | 817/817 | 0.67 (0.53–0.83) | 0.66 (0.52–0.83) |
| p-value | <0.001 | <0.001 | |
| Per SD of RTL b | 817/817 | 0.80 (0.70–0.90) | 0.79 (0.70–0.90) |
| p-value | <0.001 | <0.001 | |
| RTL quartile | |||
| Q1 (≤0.726) | 186/186 | 1 (reference) | 1 (reference) |
| Q2 (0.726–0.948) | 198/198 | 0.81 (0.61–1.08) | 0.76 (0.56–1.03) |
| Q3 (0.948–1.200) | 201/201 | 0.80 (0.60–1.06) | 0.77 (0.57–1.05) |
| Q4 (>1.200) | 232/232 | 0.54 (0.39–0.74) | 0.53 (0.38–0.74) |
| p-trend | 0.002 | 0.002 |
Abbreviations: RTL, relative telomere length; OR, odds ratio; CI, confidence interval; Q, quartile; a Adjusted for hypertension, hyperlipidemia, diabetes, hypercholesterolemia and cadmium. b We modeled RTL as a continuous variable (per one standard deviation [SD] increase). One SD of RTL = 0.347.