Skip to main content
. 2020 Mar 31;25(1):1–8. doi: 10.3746/pnf.2020.25.1.1

Table 1.

Characteristics of the selected studies included in this meta-analysis

References Country Health status Study design Sample size (control/intervention) Sex Intervention (name and daily dose) Trial duration (day) Biomarker Age (control/intervention) Results (intervention group) Jaded score
Arruda et al. (2013) Brazil Sickle cell anemia patients R/DB/PC 39/44 F/M Vit C/1,400 mg 90 CRP 22/27 Significant increase 5
Vit E/800 mg
Arruda et al. (2013) Brazil Sickle cell anemia patients R/DB/PC 39/44 F/M Vit C/1,400 mg 180 CRP 22/27 Significant increase
Vit E/800 mg
Barker et al. (2011) USA Patient with anterior cruciate ligament injury R/DB/PC 9/10 M Vit C/1,000 mg 104 CRP 36/32 No significant effect 2
Vit E/400 IU
Bruunsgaard et al. (2003) Denmark Healthy R/DB/PC 52/50 M Vit C/500 mg 1,151 CRP 59/61 No significant effect 2
Vit E/200 mg
Peairs and Rankin (2008) USA Overweight R/DB/PC 8/10 F/M Vit C/1,000 mg 7 CRP 29.9/31.6 Significant decrease 2
Vit E/800 IU
Tahir et al. (2005) Ireland Patient with aortic valvular stenosis R/SB 20/41 F/M Vit C/1,000 mg 180 CRP 70/66 No significant effect 2
Vit E/400 IU
Ullegaddi et al. (2005) UK Acute ischaemic R/SB 24/24 F/M Vit C/500 mg 7 CRP 79/76 Significant decrease 3
Stroke patients within 12 h of symptom onset Vit E/800 IU
Ullegaddi et al. (2005) UK Acute ischaemic R/SB 24/24 F/M Vit C/500 mg 14 CRP 79/76 Significant decrease 3
Stroke patients within 12 h of symptom onset Vit E/800 IU
Ullegaddi et al. (2005) UK Acute ischaemic R/SB 24/24 F/M Vit C/500 mg 90 CRP 79/76 Significant decrease 3
Stroke patients within 12 h of symptom onset Vit E/800 IU
Osman et al. (2016) Malaysia Hyper-cholesterolemic patients R/DB/PC 19/19 F/M Vit C/500 mg 360 CRP 41.3/42 No significant effect 2
Vit E/80 mg
Bloomer et al. (2007) USA Healthy persons (without prior exercise) R/DB/PC 8/7 M Vit C/1,000 mg 14 CRP 25/23 No significant effect 3
Mixed tocopherol/378 mg
Mixed tocotrinols/39.5 mg
Bloomer et al. (2007) USA Healthy persons (without prior exercise) R/DB/PC 8/7 M Vit C/1,000 mg 15 CRP 25/23 No significant effect 3
Mixed tocopherol/378 mg
Mixed tocotrinols/39.5 mg
Bloomer et al. (2007) USA Healthy persons (without prior exercise) R/DB/PC 8/7 M Vit C/1,000 mg 16 CRP 25/23 No significant effect 3
Mixed tocopherol/378 mg
Mixed tocotrinols/39.5 mg
Bloomer et al. (2007) USA Healthy persons (with prior exercise) R/DB/PC 7/8 M Vit C/1,000 mg 14 CRP 22/22 No significant effect 3
Mixed tocopherol/378 mg
Mixed tocotrinols/39.5 mg
Bloomer et al. (2007) USA Healthy persons (with prior exercise) R/DB/PC 7/8 M Vit C/1,000 mg 15 CRP 22/22 No significant effect 3
Mixed tocopherol/378 mg
Mixed tocotrinols/39.5 mg
Bloomer et al. (2007) USA Healthy persons (with prior exercise) R/DB/PC 7/8 M Vit C/1,000 mg 16 CRP 22/22 No significant effect 3
Mixed tocopherol/378 mg
Mixed tocotrinols/39.5 mg

DB, double-blinded; SB, single-blinded; PC, placebo-controlled; R, randomized; F, female; M, male.