Table 3.

“Sepsis-3” definitions and identifying features, adapted from Singer et al. [22].

Sepsis	Septic Shock
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection.	Septic shock is a subset of sepsis in which underlying circulatory and cellular metabolism abnormalities are profound enough to substantially increase mortality.
Organ dysfunction can be identified as an acute change in total SOFA score greater or equal to 2 points consequent to the infection.	Patients with septic shock can be identified with a clinical construct of sepsis with persisting hypotension requiring vasopressors and having a serum lactate level > 2 mmol/L despite adequate volume resuscitation.