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. 2020 Mar 9;18(3):152. doi: 10.3390/md18030152

Figure 2.

Figure 2

Laminarin inhibited intracellular signal transduction in ovarian cancer (OC) cells. (A–G) Immunoblotting showing the phosphorylation of cyclin D1 (A), AKT (B), P70S6K (C), S6 (D), extracellular signal-regulated kinase 1/2 (ERK1/2) (E), c-Jun N-terminal kinase (JNK) (F), and P38 (G) proteins in laminarin (0.5, 1, and 2 mg/mL)-treated OC cells. Phosphoprotein intensities were normalized to the total protein levels compared with vehicle-treated controls. *** p  <  0.001, ** p  <  0.01, and * p  <  0.05 indicate statistical significance compared with non-treated cells.