Table 5.

The overall animal activity of conotoxins conotoxin-Ac1 and conotoxin-Ac1-O6P((Mean ± SD).

Group	Sleep Latency (min)	Sleep Time (min)
control	12.55 ± 1.23	3.27 ± 1.01
conotoxin-Ac1 250µg/kg	3.62 ± 0.54 **	14.81 ± 4.69 **
conotoxin-Ac1 500µg/kg	1.64 ± 0.48 **	36.87 ± 5.82 **
conotoxin-Ac1-O6P 250µg/kg	4.15 ± 2.06 **	12.49 ± 4.28 **
conotoxin-Ac1-O6P 500µg/kg	2.03 ± 1.35 **	21.54 ± 6.72 **

** p < 0.01 vs. the control group.