Table 2.

Pharmacological properties of echinocandins.

Echinocandin	ANF [38,39]	CSF [38,40]	MCF [38,41]
Bioavailability [%]	2–7 (p.o.), 100 (iv.)	100 (iv.)	100 (iv.)
Protein binding [%]	99	95	>99
Metabolism (CYP)	–	–	3A
Half-life [h]	40–50	8	13–20
Route of elimination	hepatic	renal	hepatic
Unchanged [%]	10	1.4	<1