Table 1.
Comparison of mcr-1.1-harboring INSali25 contig with the top six IncHI2-type mcr-1-harboring plasmids showing the highest identities (>99.6%, E-value 0.0, query coverage >94.0%).
| IncHI2-Type Plasmid (bp) | Strain (MLST 1) |
Isolation Source/ Country/Year |
Identity(%) | Alignment Length (bp) | Antimicrobial Resistance Gene 2 | Plasmid GenBank Acc. No. |
|---|---|---|---|---|---|---|
|
pSE08-00436-1 (264914) |
S. enterica 08-00436 (ST28) |
Chicken skin/Germany/2008 | 99.997 | 32115 | aadA1, aadA2-type, aph(3’)-Ia-type, aph(3’’)-Ib-type, aph(6)-Id, aac(3)-IIa, blaTEM-1B, mcr-1.1, cml-type, catA1-type, sul1, sul2, sul3, tet(A), dfrA1-type | NZ_CP020493.1 |
|
p1rc4-mcr1 (239098) |
E. coli 1RC4 (ST155) |
Hajj pilgrim Stool/France/2014 | 99.994 | 32115 | aadA1, aadA12-type, aph(3’)-Ia, aph(3’’)-Ib, aph(6)-Id, blaTEM-1B, mcr-1.1, mph(A), cml-type, floR-type, sul3-type, tet(A), dfrA4 | NZ_CM008266.1 |
|
pSA186_MCR1 (241600) |
E. coli SA186 (ST131) |
Human patient urine/ Saudi Arabia (Riyadh)/2012 | 99.993 | 30522 | aadA1, aadA2-type, aph(3’)-Ia, aph(3’’)-Ib, aph(6)-Id, blaTEM-1B, mcr-1.1, mph(A), cml-type, floR-type, sul3-type, tet(A), dfrA14 | NZ_CP022735.1 |
|
pRS571-MCR-1.1 (257270) |
E. coli RS571 (ST648) |
rectal swab/Bangladesh: Dhaka/2018 | 99.993 | 29648 | aadA1, aadA2-type, aac(3)-IId-type, aph(3’)-Ia, aph(3’’)-Ib, aph(6)-Id, blaTEM-1B, mcr-1.1, mph(A), cml-type, floR-type, sul3-type, tet(A), dfrA14 | NZ_CP034390.1 |
|
pG3X16-2-2 (265575) |
E. coli G3X16-2 (ST1196) |
Human feces/China: Guangxi/2017 | 99.977 | 30043 | aadA22, aph(3’)-Ia-type, aph(3’’)-Ib, aph(6)-Id, aph(4)-Ia-type, aac(3)-IV, blaTEM-1B, blaCTX-M-65, mcr-1.1, oqxAB-type, Inu(F)-type, mph(A), floR-type, sul1-type, sul2, tet(A)-type, tet(M)-type | NZ_CP038139.1 |
|
pMCR1_025943 (265538) |
E. coli WCHEC025943 (ST410) |
Sewage/China: Sichuan, Chengdu/2017 | 99.977 | 30043 | aadA22, aph(3’)-Ia-type, aph(3’’)-Ib, aph(6)-Id, aph(4)-Ia-type, aac(3)-IV, blaTEM-1B, blaCTX-M-65, mcr-1.1, oqxAB-type, Inu(F)-type, mph(A), floR-type, sul1, sul2, tet(A), tet(M)-type | NZ_CP027202.2 |
1 MLST accordingly with Warwick scheme (http://mlst.warwick.ac.uk/mlst/dbs/Ecoli); 2 ResFinder-3.1 (Selected % ID threshold: 90%; Selected minimum length: 60%).