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. 2020 Mar 12;25(6):1285. doi: 10.3390/molecules25061285

Table 3.

ACE inhibitor peptides that have been identified.

Pre-Met SIT ACS * RMM IC50 Ref
Enzymolysis UF, GPC-HPLC, MALDI-TOF-MS TWPERPPQIP 1033.42Da 25.67 μg/mL [40]
Enzymolysis UF, GPC, HPLC (RP-HPLC), ESI YEP 407.43Da 0.29 μmol/L [24]
Enzymolysis MALDI-TOF-MS, GPC-HPLC LPGRPPIKPWPL 1353.67 Da 128.98 μg/mL [41]
Enzymolysis RP-HPLC, HPLC YVPHWDL 929Da 0.136–0.173 μm/mL [20]
Fermentation UF, UPLC-ESI-MS/MS, RP-HPLC VQTL
LGYEN
459.35Da
594.28Da
-
-
[36]
Enzymolysis UPLC-Q-TOF-MS/MS, HPLC-MS/MS EPNGLLLPQY 1142.60 Da 0.233 μm/mL [23]
Enzymolysis UPLC-MALDI-TOF-MS LY 295.19Da 0.042 μm/mL [59]
Enzymolysis UPLC-MALDI-TOF-MS YLA 366.24Da 0.396 μm/mL [59]

The Pre-met, SIT, ACS, RMM and Ref in the table refer to preparation method, separation and identification technology, amino acid sequence, relative molecular mass and reference, respectively. * The amino acid sequence is in the form of 20 single letter abbreviations, namely Gly—G, Ala—A, Val—V, Leu—L, Ile—I, Pro—P, Ser—S, Thr—T, His—H, Glu—E, Asp—D, Gln—Q, Asn—N, Lys—K, Arg—R, Cys—C, Met—M, Phe—F, Tyr—Y and Trp—W.