Skip to main content
. 2020 Mar 11;25(6):1265. doi: 10.3390/molecules25061265

Scheme 4.

Scheme 4

i: 1,3-dimetylbarbituric acid, MgSO4, CHCl3, reflux, 6 h (10a: 95%, 10b: 36%, 10c: 52%); ii: Meldrum’s acid, MgSO4, CHCl3, reflux, 6 h (11a: 87%, 11b: 50%, 11c: 98%); iii: malonitrile, MgSO4, CHCl3, reflux, 6 h (12a: 50%, 12b: 53% 12c: 61%).