Table 4.
Hazard ratios of incident CKD events by quartiles of FEV1 in women (n = 7325)
| Q4 (reference) |
Q3 | Q2 | Q1 | P value for trend | ||
|---|---|---|---|---|---|---|
| 3.31(±0.33) | 2.80(±0.08) | 2.46(±0.11) | 1.88(±0.33) | |||
| Number (n) | 7325 | 2027 | 1629 | 1933 | 1736 | – |
|
Incident CKD: Main diagnosis (n = 165) |
CKD events n (n per 1000 person-years) | 29 (0.44) | 36 (0.70) | 51 (0.89) | 49 (1.07) | |
| Unadjusted | 1.00 | 1.64 (1.01–2.67) | 2.26 (1.43–3.57) | 3.15 (1.99–4.99) | < 0.001 | |
| Adjusteda | 1.00 | 1.21 (0.73–2.01) | 1.33 (0.80–2.20) | 1.27 (0.73–2.22) | 0.403 | |
|
Incident CKD: Main or secondary diagnosis (n = 237) |
CKD events n (n per 1000 person-years) | 40 (0.61) | 52 (1.01) | 75 (1.32) | 70 (1.54) | |
| Unadjusted | 1.00 | 1.73 (1.14–2.61) | 2.45 (1.67–3.60) | 3.38 (2.29–4.99) | < 0.001 | |
| Adjusteda | 1.00 | 1.22 (0.80–1.87) | 1.31 (0.86–1.99) | 1.22 (0.77–1.94) | 0.442 |
aAdjustments: Age, baseline eGFR, height, BMI, smoking status, cholesterol, history of CVD, history of diabetes, systolic BP, physical activity, social class, ESR (log transformed), BP medication, screening year
Incident CKD events: includes both inpatient hospitalisations and outpatient diagnosis. Main diagnosis = Primary diagnosis, Main or secondary diagnosis = Primary diagnosis or 1st-3rd secondary diagnosis