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. 2020 Apr 9;7:20. doi: 10.1186/s40662-020-00184-5

Table 1.

Comparison between the subgroups of ANN group (ICRS and ICRS+CXL), in preoperative and postoperative period

Variables Group p value
ICRS ICRS + CXL
Pre-op Grade of keratoconus 2.13 ± 1.13 2.67 ± 0.89 p > 0.05
UDVA [Decimal value (LogMAR)]

0.22 ± 0.14

(0.66)

0.14 ± 0.14

(0.85)

p > 0.05
CDVA [Decimal value (LogMAR)]

0.68 ± 0.24

(0.17)

0.53 ± 0.20

(0.28)

p > 0.05
SE (D) −2.27 ± 2.92 −4.97 ± 3.82 p > 0.05
Sim-K Avg (D) 46.33 ± 2.79 48.38 ± 4.32 p > 0.05
CCT (μm) 475.63 ± 41.66 473.25 ± 42.28 p > 0.05
ThkMin (μm) 459.63 ± 45.63 456.83 ± 44.48 p > 0.05
Corneal volume (mm3) 54.53 ± 3.12 54.14 ± 2.90 p > 0.05
Total aberrations (μm) 4.44 ± 2.03 5.98 ± 2.79 p > 0.05
High Order aberrations (μm) 3.26 ± 1.76 3.98 ± 2.31 p > 0.05
Astigmatism aberrations (μm) 3.38 ± 1.28 3.78 ± 2.93 p > 0.05
Coma-like aberrations (μm) 3.16 ± 1.77 3.84 ± 2.30 p > 0.05
Spherical-like aberrations (μm) 0.81 ± 0.27 1.01 ± 0.38 p > 0.05
Post-op UDVA [Decimal value (LogMAR)]

0.37 ± 0.21

(0.43)

0.36 ± 0.22

(0.44)

p > 0.05
CDVA [Decimal value (LogMAR)]

0.78 ± 0.18

(0.11)

0.70 ± 0.24

(0.15)

p > 0.05
SE (D) −2.39 ± 2.22 −2.71 ± 2.61 p > 0.05
Sim-K Avg (D) 45.07 ± 2.28 45.50 ± 5.37 p > 0.05
CCT (μm) 478.38 ± 37.54 469.25 ± 55.85 p > 0.05
ThkMin (μm) 454.50 ± 47.66 433.75 ± 50.22 p > 0.05
Corneal volume (mm3) 55.24 ± 3.72 55.13 ± 3.07 p > 0.05
Total aberrations (μm) 3.91 ± 2.66 5.58 ± 2.72 p > 0.05
High Order aberrations (μm) 2.46 ± 0.73 3.93 ± 2.27 p > 0.05
Astigmatism aberrations (μm) 2.94 ± 2.86 3.81 ± 1.92 p > 0.05
Coma-like aberrations (μm) 2.09 ± 0.51 3.13 ± 1.78 p > 0.05
Spherical-like aberrations (μm) 1.20 ± 0.46 2.22 ± 1.65 p > 0.05

In the ANN group, considering the two subgroups ICRS group and ICRS+CXL group, there is no statistically significant difference in terms of grade of keratoconus, UDVA (uncorrected distance visual acuity), CDVA (corrected distance visual acuity), SE (spherical equivalent), Sim-K Avg (simulated mean keratometry), CCT (central corneal thickness), ThkMin (minimal thickness), corneal volume and corneal aberrations, neither in the preoperative nor in the postoperative period (p > 0.05). Visual acuity is expressed in decimal value and the corresponding LogMAR value is reported in brackets